Worm “Seizure” Movies

These and other videos are published as Williams et al. (2004) “Epileptic-like convulsions associated with LIS-1 in the cytoskeletal control of neurotransmitter signaling in Caenorhabiditis elegans” Hum. Mol. Genet. 13:2043-2059. They are available at the journal website for Human Molecular Genetics. An international press release on this work is available at the website of the Howard Hughes Medical Institute.

Quicktime video of C. elegans lis-1 mutants exhibiting epileptic-like convulsions in the presence of PTZ

Quicktime video of a C. elegans unc-43 (calmodulin kinase II) mutant exhibiting epileptic-like convulsions in the presence of PTZ

Embryonic Cell Division Movies

Quicktime video of wild-type C. elegans embryo undergoing its initial cell division

Quicktime video of nud-1 RNAi-treated C. elegans embryo

Quicktime video of lis-1 RNAi-treated C. elegans embryo