Study Guide for Exam 2
As usual, I do not expect you to know all the names of
enzymes and every intermediate molecule in a pathway. You should be able to
draw the structures and know which cofactors are involved.
My exams never simply test how well/much you can
memorize & regurgitate. They are also designed to test how much you understand.
That is, the WHY of things, the implications of the way things work in
biochemical pathways, how things are integrated in the cell, etc.
[Items in bold are more important. Those
in (parentheses) are less. But
anything on this list is fair game.]
You should know:
Ch. 20 (+ some of 15)
Rubisco
(mechanism of carboxylation and
oxygenation)
(photorespiration
and Rubisco specificity)
C3 vs.
C4 metabolism (Hatch-Slack pathway)
Oxidative
pentose phosphate pathway
(triose/Pi transport)
(starch & sucrose synthesis)
NOT
covered: phosphoglycolate pathway
Ch. 21
Acetyl-CoA
carboxylase
Fatty
acid synthase (mechanism)
(FA
desaturation)
Synthesis
of triacylglycerols and glycerophospholipids
NOT
covered: ether lipids, sterols,
isoprenoids, lipid transport (in the body), sphingolipids, headgroup synthesis,
salvage and joining to phospholipids
Ch. 22
Glutamine
synthetase (and its regulation) &
glutamate synthase
Glutamine
amidotransferases (mechanism)
Amino
acid synthesis:
Pro
& Arg synthesis
Asp
& Asn synthesis
Gly
& Ser synthesis & metabolism
(Salvage
pathways: Pro > Arg, Met > Cys)
Pyrimidine
synthesis ( > OMP > UMP >
UTP, CTP)
Purine
synthesis ( > IMP > AMP, GMP)
Ribonucleotide
reductase (mechanism)
Thymidylate
synthase (mechanism)
NOT
covered: branched-chain amino acid
(Val, Ile, Leu) synthesis, S incorporation, aromatic amino acid synthesis, His,
Lys, glutathione, porphyrins, catabolism and salvage of purines &
pyrimidines,
Channels: mechanisms of specificity and gating
Acetylcholine-gated
Na+ channel
Voltage-gated
Na+ channel
Action
potential and synaptic transmission
Insulin
pathway
PLC/PKC
pathway
Epinephrine
pathway
Vision